The observation of ?-endorphin receptors on macrophages / 中国免疫学杂志

ABSTRACT

?-endorphin (?-END) receptors on peritoneal M?s of mice and rats were investigated by radiotigand binding assay. The results have shown that there were no specific bindings on both murine and rat' s M?s. Murin M?s activited by macrophage activating factor (MAF) did not express ?-END receptor. Neither the filtration nor the gradient centrifugation method for separating the bound Iodinelabled ligand from the free ones would affect these results. These results suggest that the modulation of ?-END on M? functions might be evoked by means of alternative other than receptor mechanisms.