IDENTIFICATION OF HUMAN PAPILLOMAVIRUSES DNA IN LESIONS FROM WOMEN WITH CONDYLOMA ACUMINATA BY MOLECULAR HYBRIDIZATION / 西安交通大学学报(医学版)

ABSTRACT

HPV DNA were detected in 60 biopsies from women with condyloma acuminata (vulva 47,Vagina 12,cervix 1)by dot blot hybridiztion;physical states of 8 HPV 11 DNA were analyzed by techniques of restriction endonuclease and Southern blot hybridization. HPV 11 was found in 19biopsies of vulva (13 ). vagina (5)and cervix (1),and HPV 16 and 18 in lvaginal and 1 vulvar biopsy respectively. All of HPV 11 DNA were episomal in cells . Our results provided the data for further studying the relationship between HPV and genital cancer in our country.