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THE METHODS DETECTING VASCULAR ENDOTHELIAL GROWTH FACTOR IN HUMAN BREAST CARCINOMAS / 中国现代普通外科进展
Chinese Journal of Current Advances in General Surgery ; (4)1999.
Artículo en Chino | WPRIM | ID: wpr-535552
ABSTRACT

Objective:

To establish analysis method of vascular endothelial growth Factor(VEGF)for clinic practice.

Methods:

the expression of VEGF in breast carcinoma tissue is examined with immunohistochemistry, RT-PCR, Western blot and dot blot.

Results:

the VEGF is revealed mainly in tumor cells and extracellular matrix, molecular weight of VEGF is 46 KD, including three isoforms. In 53% of the cases the tumor tissue reveals stronger expression of VEGF than paratumor tissue.

Conclusion:

Dot blot may be used as a preliminary method for detecting VEGF in breast carcinoma tissue.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Current Advances in General Surgery Año: 1999 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Current Advances in General Surgery Año: 1999 Tipo del documento: Artículo