A case control study of using free-radical scavenger for chronic prostatitis / 中华泌尿外科杂志

ABSTRACT

Objective To evaluate the efficacy of free-radical scavenger in the treatment of chronic prostatitis (CP). Methods 117 patients with CP were randomly divided into 4 groups: group A (32 patients) were treated with free-radical scavenger, group B (32 patients) with antibiotics, group C (32 patients) with ?-blocker and group D with placebo. Microscopic examination,bacterial culture,SOD and MDA examination were conducted just before and after the procedure. Results No cure was observed in each group.18 patients were improved in group A,15 in group B,21 in group C and 2 in group D. The efficacy rate was 47.3%,46.8%,65.6% and 13.3% respectively. Compared to the placebo group, the free-radical scavenger had a significant therapeutic efficacy and had no significant difference to the antibiotic group and ?-blocker group. Conclusions The free-radical scavenger may be a useful method for the treatment of chronic prostatitis.