A preliminary study on intravesical capsaicin for the treatment of obstinate urethral syndrome / 中华泌尿外科杂志

ABSTRACT

Objective To evaluate intravesical capsaicin for the treatment of obstinate urethral syndrome in female. Methods Thirty two female patients suffering from urethral syndrome not relieved on various therapeutic methods for a long time were treated by bladder instillation of 100 ml of 100 ?mol/L capsaicin. Results 15 cases were followed up for more than 12 months with improvement in 94%.The symptoms were totally disappeared in 33% of the patients.The syndrome recurred in 53% between 3～6 months. 1 case did no response to the treatment. Bladder instillation of capsaicin induced an increase of the bladder volume.Some burning sensation was the only side effect. Conclusions Intravesical capsaicin could be a long lasting effective therapeutic method for patients with obstinate urethral syndrome.