The anti inflammatory and diuretic effects and acute toxicity of aqueous extract of psychotria morindoides hutch on rat and mice

ABSTRACT

The 11 aqueous extract of Radix Psychotria morindoides Hutch – Rubiacease with an oral dose of 10g/kg body weight of rat Has no acute and anti-inflammatory effect on carrageenin – indecued edema in hind paw, but it reduces the asbestos induced granuloma as a subchronic inflammation medel. Increases the excretion of urine up to 83% at the sixth hour after drug ingestion. DL50 of the aqueous extract could not be determined because of its very low toxicity.