Effect of Pentoxifylline on type 1 diabetes in NOD mice / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-537347
ABSTRACT
Objective To study the effect of phosphodiesterase inhibitor pentoxifylline (PTX) on type 1 diabetes in NOD mice and its possible mechanism.Methods Blood glucose, urinary glucose, insulitis and incidence of diabetes were investigated in NOD mice treated with PTX, insulitis was observed by HE staining and the expressions of IFN ?, TNF ?, IL 10 in pancreas were measured by RT PCR technique. Results The incidence of diabetes in the PTX group was 30.0% which was significantly lower than 67.9% in the control group (P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Endocrinology and Metabolism
Año:
2001
Tipo del documento:
Artículo
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