Changes and their clinical value of integrated backscatter in patients with acute myocardial infarction / 中华超声影像学杂志

ABSTRACT

Objective To explore the value of integrate d backscatter technique (IBS) in quantitative evaluation of myocardial viability and left ventricular remodeling (LVRM) in patients with acute myocardial infarction(AMI). Methods In 18 healthy subjects (control group) and 36 patients with first onset AMI, IBS images were obtained at apical long axis, 2- and 4-chamber views within one week, at 1 and 3 months after percutaneous intracoronary stenting. The dynamic changes of IBS and its cyclic variation (CVIB) at middle segments of six different walls of left ventricle were compared with normal control, and the relations of these changes with the remodeling and the function of left ventricle were analyzed. Results Based on the existence of LVRM, the patients were divided into two groups: group A without LVRM and group B with LVRM. In group A, IBS of both infarct and non-infarct segments were not significantly different from control group within one week while CVIB of infarct segments decreased significantly than that of control group. CVIB improved gradually with the recovery of LV function whereas IBS showed no change. In group B, IBS of infarct segments increased significantly than that of control group and CVIB of both infarct and non-infarct segments decreased significantly. IBS of both infarct and non-infarct segments increased gradually while only CVIB of non-infarct segments recovered. Meanwhile, ventricular aneurysm appeared and LV enlarged gradually with LV function not improved. Conclusions The dynamic changes of IBS are different in patients with AMI from normal subjects and it may be clinically useful to evaluate myocardial viability quantitatively and predict LVRM and the recovery of LV function.