Evaluation of anti-CD25 monoclonal antibody to prevent acute rejection after renal transplantation / 中国免疫学杂志
Chinese Journal of Immunology
; (12)2000.
Article
en Zh
| WPRIM
| ID: wpr-538746
Biblioteca responsable:
WPRO
ABSTRACT
Objective:To investigate the effect of anti-CD25 monoclonal antibody in preventing acute rejection after renal transplantation.Methods:71 patients were randomly divided into two groups;treatment gourp( n =26)and control group( n =45).The treatment group received anti-CD25 monoclonal antibody twice before and after renal transplantation.The occurrence of rejection postoperation and renal function and T lymphocyte subtypes were sequentially monitored.Results:The occurrence of aute rejection in treatment group in 1,3,6 and 12 months after renal transplantation was 7.7% ,19.2%,23.1% and 30.8%,while it was 15.6%,28.9%,35.6% and 46.7% in control group.There was significant difference between the two groups( P0.05 ).Conclusion:It suggests that anti-CD25 monoclonal antibody reduce the occurrence of acute rejection and have no influence on T lymphocyte subtypes.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Immunology
Año:
2000
Tipo del documento:
Article