Advances in Vascular Prosthesis in Which Lined with Genetically Modified Endothelial Cells / 中国普外基础与临床杂志
Chinese Journal of Bases and Clinics in General Surgery
;
(12)2004.
Artículo
en Chino
| WPRIM
| ID: wpr-539003
ABSTRACT
Objective To discuss the endothelial cell which was modified by exogenous anticoagulant genes contribute to the increase of antithrombosis activity of lined vascular prosthesis and the influence to other physiological functions of endothelial cells. Methods This summarized paper was made on literature review of recent years.Results The transfection of genes, including plasminogen activator (t-PA, u-PA, Urokinase), thrombomoduline (TM) and hirudin, etc, to endothelial cells resulted in not only the increase of antithrombosis activity of local vascular, but also the decrease of endothelial cell function in adherence and proliferation.Conclusion The increase of antithrombosis activity of lined vascular prosthesis has been done by exogenous genes. However, this technique ought to be studied, intensively.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Bases and Clinics in General Surgery
Año:
2004
Tipo del documento:
Artículo
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