Advances in research on ATM as a target for novel radiosensitizers / 中国癌症杂志
China Oncology
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-539454
ABSTRACT
Patients with ataxia-telangiectasia ( A-T) syndrome were charachaterized by profound hypersensitivity to ionizing radiation in clinic. Many studies have shown that this hypersensitivity possibly attributed to ATM gene whose critical compartment was ATM kinase. So inhibitors of the ATM kinase such as caffeine, pentoxifylline, methyl xanthines and 7-hydroxystaurosporine (UCN-01) were developed and have achieved a few encouraging results in basic and clinical stuides.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
China Oncology
Año:
2001
Tipo del documento:
Artículo
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