Inhibitory effect of Chinese nutgall extracts on the secretion of IL-6 from mon ocytes induced by lipopolysaccharide of Porphyromonas gingivalis / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-540678
ABSTRACT
Objective:
To observe the effects of Chinese nutgalls ex tr acts on the secretion of IL-6 from monocytes induced by lipopolysaccharide (LPS ) of Porphyromonas gingivalis (Pg).Methods:
Monocytes ob tained by separating human blood cells were stimulated with LPS of Pg at 25 ?g/ml, radioimmunoassay (RIA) was used to examine the effect of Chinese nutgal ls extracts at the concentrations of 6.25-100 ?g/ml on the secretion of IL-6 in the supernatant of the cell culture.Results:
Chinese nutgalls extracts at the concentrations(?g/ml) of 6.25,12.50, 25.00 ,50.00 and 100.00 inhibited IL-6 secretion from monocytes by(%) 34.6,46.4,48.5,52.7 and 54.9 res pectively.Conclusions:
Extracts from Chinese nutgalls may inhibit the secretion of IL-6 from monocyte induced by LPS of Pg in a dose-depend ent manner.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Practical Stomatology
Año:
2001
Tipo del documento:
Artículo
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