Experimental Study on PPAR? Ligands Regulating the Inflammatory Cytokines in Human Gallbladder Epithelial Cells / 中国普外基础与临床杂志
Chinese Journal of Bases and Clinics in General Surgery
;
(12)2003.
Artículo
en Chino
| WPRIM
| ID: wpr-541543
ABSTRACT
Objective To study the regulatory ability of peroxisome proliferator-activated receptor ?(PPAR?) ligands to the inflammatory response in human gallbladder epithelial cells. Methods Culture human gallbladder epithelial cells and identify them . Cells were treated for 24 hours with 0, 10 ?mol/L, 20 ?mol/L, 30 ?mol/L, 50 ?mol/L and 100 ?mol/L of Ciglitazone during cellular growth peak(5th day), then stimulated them with hIL-1? 5 ng/ml for 2 hours and measured the concentration of IL-6、IL-8 and TNF-? in cellular supernatants by riadioimmunoassay. Results Contrasted with control group, the expression of IL-6 and IL-8 in each test group were inhibited ((P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Bases and Clinics in General Surgery
Año:
2003
Tipo del documento:
Artículo
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