Progress in research of synaptic plasticity and long-term potentiation / 西安交通大学学报(医学版)

ABSTRACT

Long-term potentiation is an important form of synaptic plasticity and a cellular model for study of learning and memory. Long-lasting long-term potentiation is also a cellular model used in the research of long-term memory. The transformation from silent synapses to the functional ones is probably the important mechanism for the LTP maintenance. After induction, the LTP could be reversed by the physiological or artificial stimulations. Owing to the reversibility of LTP and its input-specific characteristics, it is reasonable to interfere specifically the addiction memory with particular deep brain electrical stimulation without damaging the brain functions.