Micronucleus and Chromosome Aberration in Root Tip Cell of Vicia faba Induced by Surfactants / 环境与健康杂志

ABSTRACT

Objective To study the genetic toxicity of surfactants Tween-20?Tween-80?Span-20?BE-2. Methods To take root tip cells of Vicia faba as the subjects, treated with various concentrations of surfactants to study the effect of them on the micronucleus and chromosome aberration in root tip cells of Vicia faba. Results The frequencies of micronucleus cell induced by surfactants Tween-20?Tween-80?Span-20?BE-2 were (21.34?1.31)‰, (13.44?2.66)‰, (15.29?3.16)‰ and (7.53?2.34)‰ respectively, the frequencies of chromosome aberration induced by surfactants Tween-20?Tween-80?Span-20?BE-2 were (18.16?0.50)%, (11.05?1.18)%, (23.79?1.62)% and (22.58?0.61)%, significant differences were seen compared with the control. Conclusion The results of the present paper demonstrates that surfactants Tween-20?Tween-80?Span-20?BE-2 have the effect of mutagenic agent.