Clinical significance of fatty acid synthase in non-small cell lung cancer / 中国癌症杂志
China Oncology
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-541991
ABSTRACT
Purpose:
To explore the expression of fatty acid synthase in non-small cell lung cancer and to detect its association with clinicopathological features and prognosis.Methods:
107 patients with NSCLC who underwent surgery were followed up for more than 5 years.Fatty acid synthase were evaluated by immunohistochemisctry on formalin fixed paraffin embedded tissues and compared with benign lesion and normal tissue.Multiple clinical parameters and survival were analyzed.Results:
In 107 patients with NSCLC,FAS expression was observed in 43 cases(40.2%).In contrast to benign lesions and normal tissue,FAS is significantly overexpressed in NSCLC.Survival analysis revealed that the 5-year survival rate was lower in FAS positive patients than in negative patients(16% vs 43%,p
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
China Oncology
Año:
2001
Tipo del documento:
Artículo
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