Correlation between Contrast-enhanced MRI Features and the mRNA Expression of VEGF and bFGF in Pituitary Adenomas / 实用放射学杂志
Journal of Practical Radiology
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-542366
ABSTRACT
Objective To investigate the correlation between mRNA expression of VEGF,bFGF and dynamic contrast-enhancedT_1-weighted MRI together with conventional MRI features in pituitary adenomas.Methods Conventional MRI and gadolinium-enhanced dynamic Turbo-FLASH imaging was performed preoperatively in 30 patients with histologically verified pituitary adenoms.VEGF and bFGF mRNA expression were determined in pituitary adenomas by using comparative reverse transcription-polymerase chain reaction(RT-PCR) in all patients.The correlation between mRNA expression of VEGF/bFGF and dynamic contrast-enhanced and conventional MRI featureswere studied.Results Significant difference in VEGF and bFGF mRNA expression was found among pituitary adenomas according to different signal intensity-time curve(SI-TC) type(P
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Practical Radiology
Año:
2001
Tipo del documento:
Artículo
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