Growth and/or acid production ability of Candida albicans on silicon elastomer incorporated with antifungal agents / 实用口腔医学杂志

ABSTRACT

Objective:Through monitoring the pH of the growth medium,to evaluate the growth and/or acid production ability of Candida albicans on silicon elastomer incorporated with two different antifungal agents.Methods:Antifungal agents(AntimTM-AM and Conval pag-40)were added at concentrations from 0% to 2%,and antibacterial effect of the material in saliva and serum groups were examined.The third group added nothing was served as the control.Results:Each group with 2% antifungal agents showed great inhibitory effects on the acid production and /or the growth of C.albicans.These inhibitory effects consisted of a delay in the onset of rapid pH decline,decreased with the rate of pH change and increased in minimum pH.As a result,Conval pag-40 showed a significantly greater antimicrobial effect than AntimTM-AM.Conclusion:Silicone elastomer material incorporated with antifungal agents have strong antibacterial ability and can satisfy the requirements of clinical application.