The effect of overdose fluoride on the expression of Smad3 in rat incisor / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-544918
ABSTRACT
Objective:
To study the effect of overdose fluoride on Smad3 expression during development course of Wistar rat's incisor,and then to explore pathogenesis of dental fluorosis.Methods:
20 Wistar rats(10 male rats and 10 female rats)were randomly divided into two groups.Experiment group was feed with water contained 0.1 g/L fluorin and normal group with distilled water was served as control.After 8 weeks all rats were sacrificed.Immunohistochemistry was used to observe the effect of overdose fluorin on Smad3 expression in rat's ameloblast and odontoblast.Results:
The immunohistochemistry results demonstrated that in experiment group,Smad3 expression in rat's ameloblast and odontoblast was lower than those in control group,and statistic analysis showed there were significant differences between the two groups(P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Practical Stomatology
Año:
2001
Tipo del documento:
Artículo
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