Expression of aquaporin1 in human amniotic membrane and its significance / 重庆医科大学学报

ABSTRACT

Objective:To investigate the expression,location and significance of aquaporin1(AQP1) in the tissue of amniotic membrane.Methods:Immunohistochemical method was used to examine the expression of aquaporin1 in the tissue of amniotic membrane of 12 normal full-term pregnant women,11 full-term pregnamt woman with oligohydramnios and 9 with polyhydramnios.Result:Aquaporin1 was expressed in cuboidal epithelial cells of amniotic membrane,and mainly in cytoplasm.There was but a little expression of aquaporin1 in fibroblast of amniotic membrane tissue.There was statistically significant difference of the AQP1 expression between oligohydramnios,polyhydramnios and normal full-term pregnancy women integrative optical density in amniotic membrane tissue,respectively(P