Changes of ultrastructures and respiratory function of the spinal cord mitochondrial in experimental spinal cord injury / 中国矫形外科杂志
Orthopedic Journal of China
; (24)2006.
Article
en Zh
| WPRIM
| ID: wpr-546542
Biblioteca responsable:
WPRO
ABSTRACT
[Objective]To study changes of ultrastructures and respiratory function of the spinal cord mitochondrial in experimental spinal cord injury.[Method]Forty-eight SCI models in adult SD rats were built based on modified Allen's method.Mitochondria was extracted from injuried spinal cord tissue by using modified Estabrook's method at 6h,12h and 24h after SCI.Then ultrastructural changes and respiratory function,including R3,R4,RCR,P/O were observed.[Result]Ultrastructure of mitochondria was damaged greatly.The results revealed that R3、RCR and P/O of injuried spinal cord mitochondria decreased significantly after injury compared to the normal control group(P
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WPRIM
Idioma:
Zh
Revista:
Orthopedic Journal of China
Año:
2006
Tipo del documento:
Article