STUDIES ON THE ACTIVE PRINCIPLES OF PHYTOLACCA ESCULENTA VAN HOUTTE I. THE ISOLATION AND IDENTIFICATION OF TRSTERPENOID SAPONINS / 第二军医大学学报

ABSTRACT

From the roots of phytolacca esculenta, six triterpenoid saponins were isolated. On the basis of spectral analysis and chemical properties, four of them were identified as 3-O-(?-D-glucopyranosyl-?-D-xylopyranosyl)-jaligonic acid-30-methyl ester, 3-O-?-D-xylo pyranosyl-jaligonic acid-30-methyl ester, 3-O- (?-D-glucopyranosyl-?-D-xylopyranosyl) -esculentic acid-30-methyl ester and 3-O-?-D-glucopyranosyl-jaligonic acid -30-methyl ester,and in sequence tentatively named as esculentoside"Jia""yi""bing'' and"ding" respectively.Pharmacological experiments showed that the total saponins and esculentoside "Jia" exert a considerable enhancement on phagocytic function of leucocytes and that the total saponins can promote DNA synthesis to make the DNA which was decreased by hydroxy-urea keep a normal level.