Chemical Leukoderma Improved by Low-dose Steroid Pulse Therapy
Annals of Dermatology
;
: 241-244, 2010.
Artículo
en Inglés
| WPRIM
| ID: wpr-54687
ABSTRACT
Chemical leukoderma occurs due to the toxic effect of a specific chemical preceding allergic contact dermatitis. The mechanism is either destruction or inhibition of melanocytes by the offending substance. Clinicohistopathologically, no absolute criteria can differentiate chemical leukoderma from vitiligo. However, chemical leukoderma can be diagnosed clinically by a history of repeated exposure to a known or suspected depigmenting agent at the primary site. There is no agreed treatment guideline for chemical leukoderma. We report a healthy 51-year-old man who had multiple hypopigmented macules and patches on his face, neck, arms and legs after exposure to occupationally related chemicals. The lesions were recalcitrant to topical corticosteroids, but they showed much improvement after 3 cycles of systemic steroid pulse therapy. We suggest this therapy may be a good treatment option for chemical leukoderma.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Brazo
/
Vitíligo
/
Dermatitis Alérgica por Contacto
/
Corticoesteroides
/
Pierna
/
Melanocitos
/
Cuello
/
Ocupaciones
Tipo de estudio:
Guía de Práctica Clínica
Límite:
Humanos
Idioma:
Inglés
Revista:
Annals of Dermatology
Año:
2010
Tipo del documento:
Artículo
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