Effect of ligustrazine on TGF-?1 of patients with bronchial asthma / 西安交通大学学报(医学版)

ABSTRACT

Objective To investigate the change of transforming growth factor-?1 (TGF-?1) in peripheral blood in patients with bronchial asthma and the effect of traditional Chinese medicine Ligustrazine on it. Methods We recruited 80 normal healthy people as the control group and 160 hospitalized patients, including 80 moderate cases and 80 severe cases of bronchial asthma. TGF-?1 in peripheral blood of the patients was detected by enzyme linked immunosorbent assay. The patients were treated with conventional therapy or conventional therapy added Ligustrazine; TGF-?1 in peripheral blood before and after treatment was detected and compared. Results The level of peripheral blood TGF-?1 was higher in the patient group than in the control group obviously (P