Oxidative Damage in Cultured CHL Cells Induced by Joint Action of Benzene and Formaldehyde / 环境与健康杂志

ABSTRACT

Objective To investigate the joint action of benzene and formaldehyde for oxidative damage effects on cultured CHL cells.Methods Twenty-four hours after the cultured CHL cells exposed to formaldehyde(0,0,0,0.319 75,0.319 75,0.319 75,0.639 5,0.639 5,0.639 5 ?g/ml) or(and) benzene(0,0.392,0.784,0,0.392,0.784,0,0.392,0.784 mg/ml),the level of glutathione(GSH),malondialdehyde(MDA) and the activity of superoxide dismutase(SOD) were determined.Results Twenty-four hours after formaldehyde or(and) benzene exposure,the level of GSH reduced,activity of SOD reduced significantly(P