Relationship of expressions of E-cadherin and ?-catenin proteins and gastric mucosa intestinal metaplasia and gastric carcinoma / 中国现代普通外科进展
Article
en Zh
| WPRIM
| ID: wpr-548053
Biblioteca responsable:
WPRO
ABSTRACT
Objective:To study the relationship of expressions of E-cadherin and ?-catenin proteins and gastric mucosa intestinal metaplasia and gastric carcinoma.Methods:The immunohistochemical Envision method was used to determine the expressions of E-cadherin and ?-catenin in 30 cases of simple intestinal metaplasia(SIM) ,38 cases of atypia intestinal metaplasia(AIM) and 55 cases of gastric carcinoma.Results:The reduced expression rates of E-cadherin and ?-catenin in gastric carcinoma were significantly higher than that in SIM(P0.05) .Conclusion :E-cadherin and ?-catenin proteins take part in the transformation from intestinal metaplasia to carcinoma in gastric mucosa,AIM is a kind of precancerosis of gastric carcinoma.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Current Advances in General Surgery
Año:
2009
Tipo del documento:
Article