Effect of Bisphenol A on the Structure of Spleen and the Expression of ER-? in Rats / 环境与健康杂志
Journal of Environment and Health
; (12)1992.
Article
en Zh
| WPRIM
| ID: wpr-548442
Biblioteca responsable:
WPRO
ABSTRACT
Objective To study the effect of bisphenol A on the structure of the spleen and the expression of ER-? in F344 rats. Methods Fisher 344 rats were randomly divided into control,low-dose,moderate-dose and high-dose groups,10 in each and treated with bisphenol A through gavage at the doses of 4 mg/kg,40 mg/kg and 400 mg/kg respectively,once a day for 17 consecutive weeks. In the end of the experiment,the pathological examination of the spleen was done and the expression of ER-? was detected by western blotting. Results Compared with the control,the weight of high dose group decreased (P
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Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Environment and Health
Año:
1992
Tipo del documento:
Article