EFFECTS OF ANESTHESIA ON IR-DYN A1-13 CONTENTS IN THE BRAIN, PITUITARY AND SPINAL CORD OF RATS / 第二军医大学学报

ABSTRACT

The effects of 3 anesthetics (urethane, pentobarbital and chloraiose) on the contents of dynorphin A1-13 (ir-dyn-A1-13) in the brain, pituitary and spinal cord of male rats were studied with radioimmunoassay. Under urethane anesthesia, the contents of ir-dyn- A1-13 in the brain, pituitary and spinal cord of rats were significantly reduced. When the rats were given chloralose, the contents of ir-dyn-A1-13 were markedly reduced except in the midbrain. After the rats were anesthetized with pentobarbital, the contents of ir-dyn-A1-13 were decreased apparently except in the thalamus.