THE INHIBITON OF CHLORPROMAZINE ON ACTIVATION OF TYROSINE HYDROXYLASE BY PHORBOL DIBUTYRATE / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12)1986.
Artículo
en Chino
| WPRIM
| ID: wpr-550259
ABSTRACT
Basing on the previous report, experiments proved that chlorpro-mazine decresed DOPA formation in superior cervical ganglion ( SCG ) for 50%, and formation from PDB for 60%. The work ruled out the possibilities of decrease of DOPA synthesis from the effect on N-or M-cholinergic receptor or from the influence on DOPA decarboxylase activity. So the decrease of DOPA formation was due to inhibition of protein kinase C blocking phosphorylation of tyrosine hydroxylase.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Pharmacological Bulletin
Año:
1986
Tipo del documento:
Artículo
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