A Pathological Study on 146 Biopsies of Gastric Mucosa Diagnosed as Hyperplasia and Dysplasia / 第二军医大学学报

ABSTRACT

This paper is a pathological study in which collected 146 debatable biopsies of gastric mucosa that had been diagnosed as hyperplasia, dysplasia and carcinoma microscopically. All these cases were diagnosed as hypcrplasia and dysplasia according to the Nagayo's and Ming's standards. According to the author's revised standard, all these cases should be diagnosed as gastric carcinoma. Gastrectomy were performed recently on the above cases and the pathological diagnosis were 29 gastric carcinoma in early stage, the other 117 were in middle or late. This paper indicated that a little cytoplasm, multiform nucleus, the ceils arrangment loss of polarity, vary sized atypical glandular tubules, irregular arrangment, incompleteness appeared in half or partial gland, dysplasia epithelia budding and brandling, common wall of glands, network structure, cysts formed by one or two or more dysplasia epithelia, the nucleus squeeze to side single cell in cyst wall, variant newborn dysplasia glands etc., all of these manifestation are the Iession of carcinoma. The dysplasia should only be limited to the epithelia or glands with complete base, membrane. The dysplasia epithelia and glandular structure which located in intestitial substance are considered to be infiltrate carcinoma other than dysplasia.