INDUCTION OF PROTECTIVE IMMUNITY OF SCHISTOSOMA JAPONICUM RECOMBINANT ANTIGENS IN MICE / 中国血吸虫病防治杂志
Chinese Journal of Schistosomiasis Control
; (6)1992.
Article
en Zh
| WPRIM
| ID: wpr-551513
Biblioteca responsable:
WPRO
ABSTRACT
Schistosoma japonicum recombinant antigens were used to immunize mice in order to ob-serve their protective immunity against challenge. It was assumed that the recombinant anti-gens could reduce worm burden (29. 2%- 51. 0%) and inibit the fecundity of female schisto-some (52. 1% - 74. 3%). The antibody titers increased significant 3 weeks after the first im-munization and remained high lever. The results indicated that the recombinant antigens ex-pressed in the E. coli could induce protective immunity against challenge. It might be pro-duced in large scale as an important candidate component of a multivalent vaccine against schistosomiasis japonicum.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Schistosomiasis Control
Año:
1992
Tipo del documento:
Article