THE EFFECT OF RADIX SALVIAE MILTORRHIZAE (RSM) ON LIPOPEROXIDATION OF LDL AND ISCHEMIC BRAIN INJURY IN CHOLESTEROL FED RABBITS / 解放军医学杂志

ABSTRACT

The blood lipids and lipid peroxide (LPO) were analysed in rabbits fed with 1% cholesterol in feeding ( n =19) and with standard feeding ( n =15) after 5 weeks of feeding.The plasma LDL was isolated and ox LDL was obtained by thin layer chromatography (TLC).Cerebral ischemia was induced by ligation of left common carotid artery.The antioxidation and antiischemia injury property of RSM was also observed with TLC and electron microscopy.The results showed that the plasma LPO,FFA,CH and PL levels in 1% cholesterol fed rabbits were much higher than those of rabbits with standard feeding( P