Clinical Analysis of Supratentorial Primitive Neuroectodermal Tumor

ABSTRACT

Fifteen patients with primitive neuroectodermal tumors were reviewed. Because of ongoing nosological difficulty, we include in this series only those tumors which are located in the cerebral hemisphere, and are composed of predominantly undifferentiated neuroepithelial tumor with or without glial or neuronal differentiation. The 20 months cumulative survival rate by Kaplan-Meir method was 40% and only two patients had a long term survival more than 5 years in this series. The prognosis of the patients with cerebral PNETs remains poor despite of treatment including surgical resection. Radiation therapy and/or chemotherapy. The histological features and the extent of surgical resection did not influence the patient's survival. But visible total resection afforded better control of local disease of the primary site.