Humoral immune response to gene vaccine against adr hepatitis B virus / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-552227
ABSTRACT
Objective:
To construct HBV adr gene vaccine pCMVS 2-S and to observe the specific humoral immune responses in C57BL/6 mice after gene immunization.Methods:
The HBV gene vaccine was injected into tibialis anterior muscles of C57BL/6 mice. ELISA was used to detected the anti-HBs antibody in mice sera at various time points after gene transfer.Results:
Anti-HBs in sera of mice was tested positive 1 week after plasmid injected, the level of antibody peaked 4 weeks later, and kept high titer for at least 2 months.Conclusion:
The good response of humoral immunity can be induced by injection of pCMVS 2-S in C57BL/6 mice.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Academic Journal of Second Military Medical University
Año:
2001
Tipo del documento:
Artículo
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