Development of tumor promoter testing model with transfected human bronchial epithelial cells harboring c-Ha-ras~(V12G) / 第二军医大学学报

ABSTRACT

1 ?mol/L,24 h); (3) With the development of neoplastic transformation, the resistance to terminal differentiation induced by some promoter increased till the promoter became mitogenic. Conclusion: The development of transfected cells provides a powerful and convenient model for detecting potential tumor promoters and research on the mechanisms of promotion tumor.