Therapeutic effect of glucomanan on experimental diabetic mice / 中国药理学通报

ABSTRACT

AIM To observe the therapeutic effect of glucomanan on diabetic mice. METHODS The diabetic mice induced by alloxan model was established. The mices were randomly divided into the control and treated group to test level of blood glucose respectively. RESULTS At doses of 100,200 mg?kg -1 ig 1 and 4 h ahead of time,Glucomanan markedly reduced blood glucose level;At doses of 100, 200 mg?kg -1 ig,it markedly reduced blood glucose level of diabetic mice induced by alloxan;Useing glucomanan 100 mg?kg -1 ig bid?3 d constantly reduced amount of water-drinking. CONCLUSION Glucomanan may have significant effect on diabetic mice induced by alloxan.