Solitary pulmonary nodules:quantitative investigation with dynamic MRI / 中华放射学杂志

ABSTRACT

Objective To evaluate the diagnostic efficacy of contrast enhanced dynamic MRI in differentiating benign from malignant solitary pulmonary nodules (SPNs) Methods A prospective study was undertaken in forty four patients with SPNs using contrast enhanced dynamic MRI Patterns of Time Signal Intensity Curve (T SI Curve) were assessed Steepest Slope (SS), Peak Height (PH) and the change rates in signal intensity at the first (E 1), second (E 2), and fourth (E 4) minute of T SI curve were calculated Results Malignant nodules and inflammatory nodules showed higher SS [(4 44?1 40) %/s,(3 99?0 71)%/s, (0 86? 0 37)%/s, P