The proliferation and apoptosis of smooth muscle cells after implantation of NiTi radioactive stents in the rabbits' aortas / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
;
(12)2002.
Artículo
en Chino
| WPRIM
| ID: wpr-553026
ABSTRACT
Objectives To investigate the proliferation and apoptosis of smooth muscle cells(SMCs) after implantation of NiTi radioactive stents. Methods Radioactive and nonradioactive stents were implanted in abdominal aortas of 76 rabbits.The proliferation and apoptosis of SMCs were observed using immunohistochemistry and TUNEL.Results (1) Neointima areas on radioactive stents were less than those on nonradioacvtive stents at 1-month and 3-month respectively (P0 05).(2)The expressions of PCNA were lower in radioactive stent groups at different times compared with those of controls(P0.05).Conclusions (1) Radioactive stents can reduce the neointima areas on the implanted stents.(2)Radioactive stents can inhibit the proliferation of SMCs.(3)Radioactive stents promote the apoptosis of SMCs.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Practical Internal Medicine
Año:
2002
Tipo del documento:
Artículo
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