IMMUNOHISTOCHEMISTRY STUDY AND LEVELS OF ENDOTHELIN-1 IN GASTRIC MUCOSA OF COLD-RESTRAINT-STRESS RATS / 解放军医学杂志
Medical Journal of Chinese People's Liberation Army
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-553053
ABSTRACT
To investigate the role of ET 1 in the pathogenesis of SU, a model was established by cold restraint stress(CRS) inducing rat ulcer, immunohistochemistry(IHC)ABC method and radioimmunoassay(RIA) methods were used to determine ET 1 content and to study the expression and location of ET 1 in stomach of normal and CRS rats,and to evaluate the ulcer index(UI). IHC showed that ET 1 was stained as brownish grains,localized in the cytoplasm of vascular endothelial cells, stomach smooth muscle cells, gastric epithelial and vascular smooth muscule cells around lamina muscularis mucosae in stomach. The proportion of ET 1 positive cells was significantly higher in 3h poststress gastric mucosa than in normal gastric mucosa in rats by IHC( P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Medical Journal of Chinese People's Liberation Army
Año:
2001
Tipo del documento:
Artículo
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