Clinical efficacy analysis on treatment of unstable angina pectoris with low-molecular-weight heparins calcium / 重庆医学

ABSTRACT

Objective To investigate the clinical efficacy and safety on treatment of unstable angina pectoris (UAP) with low-molecular-weight heparins calcium .Methods 64 cases in our hospital from February 2012 to January 2013 with UAP were random-ly divided into treatment group and control group ,and 32 cases in each group .The control group was treated with routine drugs such as aspirin ,and the treatment group was treated with low-molecular-weight heparins calcium on the basis of routine therapy . The clinical efficacy and safety were evaluated by the frequency and duration of angina attacks ,the improvement of electrocardio-gram(ECG) and adverse reactions .Results The frequency and duration of angina attacks of the two groups were significantly re-duced and the performances of ECG were improved .The clinical improvement and performance of ECG were better in treatment group than those in the control group(P<0 .05) .And the total efficiency of the treatment group and control group were 93 .8%(30/32) and 84 .4% (27/32) ,respectively ,the difference had statistically significant (P<0 .05) .There was no serious adverse reac-tion in the two groups .Conclusion Low-molecular-weight heparins calcium can effectively control the frequency and duration of UAP and has less adverse reaction in treatment of UAP .It is worthy to be recommended in clinical .