THE EXPERIMENTAL STUDY ON THE ANTI-AGING AND ANTI-STRESS CAPACITIES OF QUEEN BEE LARVA / 营养学报

ABSTRACT

Objective: To evaluate the anti-aging, anti-fatigue, and anti-coldness effects of Queen Bee Larva (QBL) Methods: 1. American filth flies were divided into control group, QBL groups fed with 5%, 10%, 20%, 40% QBL and D-galactose groups, and the average and the highest life-span were recorded. 2. NIH mice were divided into control group, QBL groups fed with 1/3, 1/6 QBL, and the anti-fatigue, anti-coldness, anti-stress capacities and skin hydroxyproline were detected. Results: The average life-span of the male flies was longer in the 5%～20% QBL fed groups and in the 40% QBL with D-galactose fed group than in the others; The anti-fatigue effect was significantly higher in the mice of 1/3 QBL fed than in the others; The skin hydroxyproline was significantly higher in the male mice fed QBL than that in the control. The decrease of body temperature in cold condition was lower in the mice fed QBL than that in the control. Conclusion: QBL has distinct life-prolonging and anti-aging effects in male filth flies and delay skin-aging, and improve the anti-fatigue and anti-coldness capacity in mice.