Analysis of the correlation of the prognosis and blood lipids of heart failure in patients with coronary heart disease / 中国基层医药

ABSTRACT

Objective To investigate the relationship between the prognosis of patients with coronary heart disease in elderly heart failure between lipid levels .Methods 720 cases of coronary heart disease in elderly patients with heart failure ,according to the survival of the follow-up period were divided into survival group and death group , comparing lipid levels in each group of patients , the use of multivariate Cox regression analysis to investigate the effects of lipids in elderly patients with heart failure ,coronary artery disease prognosis .Results Age group of death , old myocardial infarction ( OMI ) , the probability of occurrence of atrial fibrillation , anemia was significantly higher than that of the survival group (χ2 =5.626,4.597,5.632,6.461,all P<0.05),HDL-C,EF,ACEI/ARB and statins was significantly lower than those of the survival group (t=10.725,9.563,8.457,9.170,P<0.05 or P<0.01).An-giotensin-converting enzyme inhibitors ( ACEI)/angiotensin Ⅱreceptor antagonists ( ARB) would help to improve the prognosis(r=0.678,P<0.01),whereas low levels and low levels of HDL-C,NYHAⅢ-grade Ⅳ,age was a risk fac-tor(r=1.052,2.298,2.586,all P<0.01).Conclusion There is a close contact between HDL-C and prognosis of heart failure in elderly patients with coronary heart disease ,in order to improve the prognosis of patients ,it can be ap-propriately managed to elevate HDL-C levels.