Susceptibility testing of yeasts to combination of amphotericin B and 5-flucytosine in vitro according to M27-A method / 第二军医大学学报

ABSTRACT

This article is to study the interaction between amphotericin B and 5-flucytosine to yeasts in vitro. The checkerboard microdilution method was applied to study in vitro interaction according to M27-A method of NCCLS. Twenty-eight strains of yeasts were used for combination study. Compared with the single agents,there were significant reductions in the geometric mean of the minimal inhibitory concentration of the combination(P