Detection of eosinophil granulocyte 1 and 2 in lung tissue from cases died of as thma / 中国实用内科杂志

ABSTRACT

Objectives To investigate the eosinophil in t he lung of patients died of asthmatic attack.Methods All samples were divided into three groups.G roup A died of asthmatic attack,Group B once had asthmatic history,died of non-asthmatic attack,Group C had no asthmatic history.Immunohistochemistry me thod was used to st udy the positive cells of EG 1 and EG 2 in lungs. Results The number of positive cells of EG 1 and EG 2 in the l ung died o f asthmatic attack was significantly higher than the other two groups.T here was no difference between Group B and Group C.There was no difference be tw een the larger bronchial and smaller bronchial and lung parenchyma.However,th e number of positive cells of EG 2 in the smaller bronchial and lung parenchyma was higher than that in the larger bronchi.Conclusion A large amount of eosinophiles infiltrate into the lung and airway of cases died of asthmatic attack,and mainly in the small er bronchi and lung parenchyma.