La accumulation and microstructure change of leg bones of rats fed with La(NO_3)_3 in low dosage for a long term / 北京大学学报(医学版)
Journal of Peking University(Health Sciences)
;
(6)2003.
Artículo
en Chino
| WPRIM
| ID: wpr-554509
ABSTRACT
Objective:
To study La accumulation and microstructure change of leg bones of rats fed with La(NO 3) 3 in low dosage for a long term.Methods:
After the rats were fed by La(NO 3) 3 in dosage of 2 mg?kg -1 ?d -1 for 6 months, the contents of La and Ca,P in the leg bones were determined by ICP MS and spectrophotometry; the microstructure changes of the leg bones were investigated by electron microscopy and X ray powder diffraction.Results:
In the leg bones of tested rats, the contents of La and P increased greatly, and those of Ca did not change obviously, so that Ca/P ratio values decreased in comparison with the control group.Conclusion:
La was accumulatied in the rat leg bones and the change of bone microstructure induced after the rats were fed with La(NO 3) 3 in low dosage for a long term.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Peking University(Health Sciences)
Año:
2003
Tipo del documento:
Artículo
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