Echocardiographical study on physiological characteristics of ventricular diastolic function in normal individual / 解放军医学杂志

ABSTRACT

Objective To investigate the regularity of changes an d the base line of physiological deficiency of ventricular diastolic function in normal individuals. Methods Non-invasive echocardiography was employed for monitoring hemodynamics of the ventricular diastolic function in n ormal individuals. 240 volunteers were divided into four groups by age, i.e. juv enile, youth, middle-aged and elderly groups. Items of examination included the diameter of cardiac chambers by two-dimensional (2D) echogram, velocity of dia stole of ventricular wall by M mode, velocity and ratio of blood flow at left an d right atrio-ventricular valves and pulmonary vein by spectral Doppler, fillin g phase and duration of filling of ventricles in diastolic phase by color Dopple r. Results Of mitral valve, tricuspid valve and pulmonary vein, a series of dynamic parameters of blood flow were correlated closely with the a ge. The ventricular diastolic function of normal person deteriorated physiologic ally with the passage of years, characterized by a normal stage in juvenile and young ages, compliant decreased stage in middle-age, and declined functional st age in aged. The declination course started in the left ventricle prior to the r ightventaide. Conclusion The results of the present study may b e helpful for further clinical researches on the mechanisms of changes in human ventricular diastolic function.