Effect of uroacitides on the expression of cyclin D1 of breast cancer cells / 解放军医学杂志
Medical Journal of Chinese People's Liberation Army
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-557331
ABSTRACT
Objective To investigate the effect of CDA-Ⅱ on t he expression of cyclin D1 of breast cancer cells. Methods The br east carcinoma cell lines MCF-7 and MDA-MB-231 were cultured in vitro tog ether with CDA-Ⅱ, with retinoic acid as positive control, and the effect of CD A-Ⅱ on the growth curve as well as the expression of cyclin D1 of breast carci noma cell lines was observed. Results CDA-Ⅱ may reduce the gr owth of MCF-7 and MDA-MB-231, cripple their proliferative ability and inhibit the cyclin D1 expression of breast cancer cell lines. Conclusion CDA-Ⅱ may inhibit the growth and proliferation of MCF-7 and MDA-MB-231, reduce the expression of breast carcinoma cell cyclin D1, hence showed a good a pplied prospect for the treatment of breast carcinoma.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Medical Journal of Chinese People's Liberation Army
Año:
2001
Tipo del documento:
Artículo
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