Progression on pathology and molecular pathology of pancreatic carcinoma / 第二军医大学学报

ABSTRACT

The incidence of pancreatic cancer is increasing and it ranks 7th in all cancer-related deaths in China.Pancreatic carcinoma is characterized by extremely poor prognosis and rapid progression, with no improvement in the 5-year survival rate over the last decade. Surgical resection remains a major treatment for patients with pancreatic cancer, but effective comprehensive treatments are still needed. Current researches of pancreatic cancer pathology mainly focus on the molecular mechanism of pancreatic cancer development, oncogenes and suppressor genes, and invasion and metastasis. It is also very important to search for new markers for early diagnosis and prognosis and to develop novel therapeutic targets. This paper presents the recent progression of pathology and molecular pathology of pancreatic carcinoma.