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Hair Growth Promoting Potential of Phospholipids Purified from Porcine Lung Tissues
Biomolecules & Therapeutics ; : 174-179, 2015.
Artículo en Inglés | WPRIM | ID: wpr-55791
ABSTRACT
BP201, porcine lung tissue-derived phospholipids, consists of phosphatidylcholine as a major phospholipid species. BP201 promoted hair growth after application onto the shaved backs of BALB/c and C3H mice. Its effect was enhanced when applied together with minoxidil (MNX) in C3H mice. When the tissue specimens prepared from the shaved skins of BP201-treated and control mice were microscopically examined, the total numbers of hair follicles in both anagen and telogen phases of BP201-treated mice were significantly higher than those of control mice. The numbers of hair follicles in the anagen phase of BP201-treated mice were also higher than those of control mice. In combination with MNX, BP201 further increased the total number of hair follicles, but did not alter the percentage of hair follicles in the anagenic phase. BP201 also increased the proliferation of human hair follicle dermal papilla cells. Collectively, BP201 possesses hair growth promoting potential, which would suggest its use singly or in combination for hair growth products.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Fosfatidilcolinas / Fosfolípidos / Piel / Folículo Piloso / Cabello / Pulmón / Ratones Endogámicos C3H / Minoxidil Límite: Animales / Humanos Idioma: Inglés Revista: Biomolecules & Therapeutics Año: 2015 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Fosfatidilcolinas / Fosfolípidos / Piel / Folículo Piloso / Cabello / Pulmón / Ratones Endogámicos C3H / Minoxidil Límite: Animales / Humanos Idioma: Inglés Revista: Biomolecules & Therapeutics Año: 2015 Tipo del documento: Artículo