Roles of different n-6/n-3 polyunsaturated fatty acid ratio in gap junctional intercellular communication in breast cancer cell lines / 第三军医大学学报
Journal of Third Military Medical University
;
(24)1983.
Artículo
en Chino
| WPRIM
| ID: wpr-558277
ABSTRACT
Objective To examine the effects of different n-6/n-3 polyunsaturated fatty acid(PUFA) ratio in gap junctional intercellular communication (GJIC) in breast cancer cell lines. Methods After MCF-7(ER + )and MDA-MB-231(ER - )cells were treated respectively with n-6/n-3 polyunsaturated fatty acid ratio (1-10), Ki-67 expression in nuclear by immunocytochemistry, connexin 26 and 43 expression in cytoplasm and membrane by Western blotting, and GJIC by scrape-loading dye transfer method were performed. Results Immunocytochemistry showed that pure n-6 and 10∶1 n-6/n-3 increased Ki-67 expression (P
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Third Military Medical University
Año:
1983
Tipo del documento:
Artículo
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